Patient-specific CFD simulation of intraventricular haemodynamics based on 3D ultrasound imaging. Issue 1 (December 2016)

• Record Type: Journal Article
• Authors: Bavo, A.; Pouch, A.; Degroote, J.; Vierendeels, J.; Gorman, J.; Gorman, R.; Segers, P.
• Is Part Of: Biomedical engineering online. Volume 15:Issue 1(2016)
• Page Start: 1
• Page End: 15
• Publication Date: 2016-12
• Subjects: CFD model with prescribed moving boundaries -- Real-time transesophageal ultrasound images -- Patient-specific modeling -- Intraventricular flow; Biomedical engineering -- Periodicals; 610.2805
• DOI: 10.1186/s12938-016-0231-9
• Languages: English
• ISSNs: 1475-925X

Abstract

Abstract Background The goal of this paper is to present a computational fluid dynamic (CFD) model with moving boundaries to study the intraventricular flows in a patient-specific framework. Starting from the segmentation of real-time transesophageal echocardiographic images, a CFD model including the complete left ventricle and the moving 3D mitral valve was realized. Their motion, known as a function of time from the segmented ultrasound images, was imposed as a boundary condition in an Arbitrary Lagrangian–Eulerian framework. Results The model allowed for a realistic description of the displacement of the structures of interest and for an effective analysis of the intraventricular flows throughout the cardiac cycle. The model provides detailed intraventricular flow features, and highlights the importance of the 3D valve apparatus for the vortex dynamics and apical flow. Conclusions The proposed method could describe the haemodynamics of the left ventricle during the cardiac cycle. The methodology might therefore be of particular importance in patient treatment planning to assess the impact of mitral valve treatment on intraventricular flow dynamics.