A prospective hospital study of alcohol use disorders, comorbid psychiatric conditions and withdrawal prognosis. Issue 1 (December 2016)

• Record Type: Journal Article
• Authors: Nubukpo, Philippe; Girard, Murielle; Sengelen, Jean-Marie; Bonnefond, Sophie; Varnoux, Aurélien; Marin, Benoît; Malauzat, Dominique
• Is Part Of: Annals of general psychiatry. Volume 15:Issue 1(2016)
• Page Start: 1
• Page End: 11
• Publication Date: 2016-12
• Subjects: Alcohol -- Psychiatry -- Comorbidity -- Withdrawal -- Abstinence -- Psychiatric care; Psychiatry -- Periodicals; Mental Disorders -- Periodicals; 616.89005
• DOI: 10.1186/s12991-016-0111-5
• Languages: English
• ISSNs: 1744-859X

Abstract

Abstract Background The objective of this study was to describe the profile and alcoholic status of a population with alcohol use disorders (AUD) requesting help from a psychiatric hospital to stop drinking, as well as their clinical outcome and care consumption over the 2 years following the request. Methods The visits were conducted at baseline (M0) and at 6, 12, 18 and 24 months (M6, M12, M18, M24). Demographic, clinical and psychometric data [Beck Depression Inventory (BDI), AUDIT questionnaire, Global Assessment of Functioning (GAF) scale], and information regarding the use of psychiatric care and therapeutics were collected. Results The 330 subjects included were mostly male, aged 45.2 ± 10.2 years with an employment rate of 55.4 %, living alone (69.1 %), with a psychiatric comorbidity (60.9 %), especially depressive, and with few somatic complications. Their global functioning was poor (GAF score 49.14 ± 15.6), and less than 10 % were addicted to another substance. The abstinence rate at 24 months was 41.4 %, but only 23 % (20) abstained continuously between M0 and M24, and 66.7 % (58) intermittently. The likelihood of abstinence at M24 was greater for females aged over 60 years. The BDI score decreased significantly between M0 and M24. In all, 56.2 % of the participants were re-hospitalized after weaning, but were not integrated in long-term medical care. Conclusions Abstinence after alcohol withdrawal fluctuated over time indicating the need for long-term support. The treatment of AUD should not target total, continuous abstinence. Prognostic profiles combining socio-demographic, clinical and biological indicators must be established.