Aerobic oxidative synthesis of 3, 5-disubstituted isoxazoles directly from α, β-unsaturated ketones. (1st October 2016)

• Record Type: Journal Article
• Authors: Li, Zheng; Wen, Gong; Fu, Rugang; Yang, Jingya
• Is Part Of: Journal of chemical research. Volume 40:Number 10(2016)
• Page Start: 643
• Page End: 644
• Publication Date: 2016-10-01
• Subjects: Chemistry -- Research -- Periodicals; Chemistry -- Periodicals; 540.5
• DOI: 10.3184/174751916X14744677622496
• Languages: English
• ISSNs: 1747-5198

Abstract

Using an efficient aerobic oxidative method, the synthesis of ten 3, 5-disubstituted isoxazoles by treatment of α, β-unsaturated ketones with hydroxylamine and NaOH at room temperature has been achieved.