Stereoselective total synthesis of (−)-conduramine F-1 via chiral 1, 3-oxazine. Issue 18 (6th May 2015) - Kim, Jin-Seok
Abstract: Total synthesis of (−)-conduramine F-1 from commercially availabled -serine was achieved. The key steps in this strategy were palladium(0)-catalyzed stereoselective intramolecular oxazine formation, extension of the chirality of anti, syn -oxazine, and Wittig and ring-closing metathesis reactions. Graphical abstract: