Two new fluorescent Zn2+ sensors exhibiting different sensing mode with subtle structural changes. Issue 5 (4th May 2017)

• Record Type: Journal Article
• Authors: Mehdi, Hassan; Pang, Hongchang; Gong, Weitao; Wajahat, Ali; Manivannan, Kalavathi Dhinakaran; Shah, Shaheen; Ye, Jun-wei; Ning, Guiling
• Is Part Of: Supramolecular chemistry. Volume 29:Issue 5(2017)
• Page Start: 378
• Page End: 386
• Publication Date: 2017-05-04
• Subjects: Fluorescence -- chemosensor -- recognition -- zinc -- conformation; Macromolecules -- Periodicals; Supramolecular chemistry -- Periodicals; 547.005
• DOI: 10.1080/10610278.2016.1242730
• Languages: English
• ISSNs: 1061-0278

Abstract

Abstract: Two novel receptorsHL-1 andHL-2 without and with hydroxyl groups were designed and synthesised. Both receptors showed highly selective coordination towards Zn 2+ and exhibited diverse sensing behaviour due to the structural variations.HL-1 showed monotonous 'turn-on' response towards Zn 2+ whileHL-2 displayed highly Zn 2+ sensitive 'turn on' and 'ratiometric' properties. Detailed Job plot experiment, single crystal data, 1 H NMR, ESI-MS, UV–vis and density functional theory calculation studies were conducted to understand the binding modes ofHL-1 andHL-2 with Zn 2+ . These results revealed the binding stoichiometric ratio between receptors and Zn 2+ were 1:1 with low detection limits and high binding constants. Abstract : Two novel receptorsHL-1 andHL-2 without and with hydroxyl groups were designed and synthesised via TCR reaction. Both of them showed selective coordination to Zn 2+ ions but exhibited incongruent sensing mode due to structural variations.HL-1 showed monotonous 'turn-on' whereasHL-2 displayed highly sensitive 'turn on' and 'ratiometric' properties towards Zn 2+ .