Monoterpenes and sesquiterpenes from the marine sediment-derived fungus Eutypella scoparia FS46. Issue 2 (1st February 2017)

• Record Type: Journal Article
• Authors: Liu, Hong-Xin; Zhang, Ling; Chen, Yu-Chan; Sun, Zhang-Hua; Pan, Qing-Ling; Li, Hao-Hua; Zhang, Wei-Min
• Is Part Of: Journal of Asian natural products research. Volume 19:Issue 2(2017)
• Page Start: 145
• Page End: 151
• Publication Date: 2017-02-01
• Subjects: Eutypella scoparia -- eutypellol A -- eutypellol B; Materia medica -- Asia -- Periodicals; Pharmacognosy -- Asia -- Periodicals; Medicinal plants -- Asia -- Periodicals; Medicine, Oriental -- Asia -- Periodicals; 615.321095
• DOI: 10.1080/10286020.2016.1189906
• Languages: English
• ISSNs: 1028-6020

Abstract

Abstract: Eutypellol A (1 ), the first norsesquiterpenoid of sequicarene family, as well as eutypellol B (2 ), a rare 7-methyl oxidized 2-carene derivative, and one new natural product 2-(2-hydroxy-4-methylcyclohex-3-enyl)propanoic acid (3 ), along with eight known terpenoids, were isolated from the marine sediment-derived fungus Eutypella scoparia FS46 collected from the South China Sea. Their structures were established on the basis of extensive spectroscopic analysis. Compounds1 –3 were evaluated for their antibacterial activities against Staphylococcus aureus and cytotoxic activities against MCF-7, NCI-H460, and SF-268 tumor cell lines.