The IGS Standard Operating Procedure for Automated Prokaryotic Annotation. Issue 2 (March 2011)

• Record Type: Journal Article
• Authors: Galens, Kevin; Orvis, Joshua; Daugherty, Sean; Creasy, Heather; Angiuoli, Sam; White, Owen; Wortman, Jennifer; Mahurkar, Anup; Giglio, Michelle
• Is Part Of: Standards in genomic sciences. Volume 4:Issue 2(2011)
• Page Start: 244
• Page End: 251
• Publication Date: 2011-03
• Subjects: Institute for Genome Sciences -- functional annotation -- structural annotation -- microbial genomics -- prokaryotic genomics -- annotation pipeline -- pFunc -- Glimmer -- HMM -- BER -- Ergatis -- Manatee -- IGS Annotation Engine; Genomics -- Periodicals; Genomics -- Periodicals; Genomics; Periodicals; 572.8605
• DOI: 10.4056/sigs.1223234
• Languages: English
• ISSNs: 1944-3277

Abstract

Abstract The Institute for Genome Sciences (IGS) has developed a prokaryotic annotation pipeline that is used for coding gene/RNA prediction and functional annotation ofBacteria andArchaea . The fully automated pipeline accepts one or many genomic sequences as input and produces output in a variety of standard formats. Functional annotation is primarily based on similarity searches and motif finding combined with a hierarchical rule based annotation system. The output annotations can also be loaded into a relational database and accessed through visualization tools.