Plasma calprotectin level: usage in distinction of uncomplicated from complicated acute appendicitis. Issue 1 (December 2016)

• Record Type: Journal Article
• Authors: Cikot, Murat; Peker, Kivanc; Bozkurt, Mehmet; Kocatas, Ali; Kones, Osman; Binboga, Sinan; Gedikbasi, Asuman; Alis, Halil
• Is Part Of: World journal of emergency surgery. Volume 11:Issue 1(2016)
• Page Start: 1
• Page End: 6
• Publication Date: 2016-12
• Subjects: Acute appendicitis -- Plasma Calprotectin -- Uncomplicated acute appendicitis -- Complicated acute appendicitis; Surgical emergencies -- Periodicals; Surgery -- Periodicals; 617.026
• DOI: 10.1186/s13017-016-0062-9
• Languages: English
• ISSNs: 1749-7922

Abstract

Abstract Background The aim of this study was to identify the diagnostic role of plasma calprotectin value for a distinction of presence acute appendicitis and the indifference of uncomplicated from complicated acute appendicitis. Methods Plasma calprotectin, white blood cell and C-reactive protein values of 89 patients, who have undergone laparoscopic appendectomy between January 2013 and May 2013 were evaluated. Results Calprotectin was 91 ng/mL (range 45–538) for acute appendicitis and 47 ng/ml (range 28–205) for the control group. There was a positive, statistically significant relation between calprotectin and C-reactive protein values (r = 0. 292p = 0. 001, respectively). There was no statistically significant difference was determined between calprotectin and white blood cell values (r = 0. 142p = 0. 187, respectively). CRP and Cal values were significantly higher in patients with a complicated AA group than in those with uncomplicated AA (p = 0. 014, p = 0. 0001, respectively) whereas white blood cell counts did not differ significantly between two groups (p = 0. 164). Conclusion Plasma calprotectin levels were increased in patients with acute appendicitis and should use in a distinction of uncomplicated from complicated acute appendicitis patients.