Copper‐Catalyzed Carbotrifluoromethylation of Unactivated Alkenes Driven by Trifluoromethylation of Alkyl Radicals. Issue 5 (21st March 2019)
- Record Type:
- Journal Article
- Title:
- Copper‐Catalyzed Carbotrifluoromethylation of Unactivated Alkenes Driven by Trifluoromethylation of Alkyl Radicals. Issue 5 (21st March 2019)
- Main Title:
- Copper‐Catalyzed Carbotrifluoromethylation of Unactivated Alkenes Driven by Trifluoromethylation of Alkyl Radicals
- Authors:
- Zhang, Zhenzhen
Zhu, Lin
Li, Chaozhong - Abstract:
- Summary of main observation and conclusion: We report herein an unprecedented protocol for radical carbotrifluoromethylation of unactivated alkenes. With Cu(OTf)2 as the catalyst, the reaction of unactivated alkenes, TMSCF3 and activated alkyl chlorides at room temperature provides the corresponding carbotrifluoromethylation products in satisfactory yields. Directed by trifluoromethylation of alkyl radicals, the method exhibits an excellent regioselectivity that is opposite to those driven by CF3 radical addition. Abstract :
- Is Part Of:
- Chinese journal of chemistry. Volume 37:Issue 5(2019)
- Journal:
- Chinese journal of chemistry
- Issue:
- Volume 37:Issue 5(2019)
- Issue Display:
- Volume 37, Issue 5 (2019)
- Year:
- 2019
- Volume:
- 37
- Issue:
- 5
- Issue Sort Value:
- 2019-0037-0005-0000
- Page Start:
- 452
- Page End:
- 456
- Publication Date:
- 2019-03-21
- Subjects:
- radical reactions -- alkenes -- trifluoromethylation -- copper -- regioselectivity
Chemistry -- Periodicals
540.5 - Journal URLs:
- http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1614-7065 ↗
http://onlinelibrary.wiley.com/ ↗ - DOI:
- 10.1002/cjoc.201900075 ↗
- Languages:
- English
- ISSNs:
- 1001-604X
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3180.299500
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 9853.xml