Six‐month outcomes after restrictive or liberal transfusion for cardiac surgery (TRICS III trial). Issue 2 (11th April 2019)

• Record Type: Journal Article
• Authors: Estcourt, L. J.; Roberts, D. J.
• Is Part Of: Transfusion medicine. Volume 29:Issue 2(2019:Apr.)
• Page Start: 77
• Page End: 79
• Publication Date: 2019-04-11
• Subjects: cardiac surgery -- randomised‐controlled trial -- red cell transfusions; Blood -- Transfusion -- Periodicals; 615.39
• DOI: 10.1111/tme.12596
• Languages: English
• ISSNs: 0958-7578

Abstract

SUMMARY: Clinical question: Is transfusing red cell components using a restrictive transfusion threshold (Hb < 75 g L −1 ) as safe as a liberal transfusion threshold (Hb < 95 g L −1 in intensive care and < 85 g L −1 outside intensive care) during and after cardiac surgery for adults at moderate to high risk of death? Evidence from trial: In adults undergoing cardiac surgery who were at moderate to high risk for death, using a restrictive red‐cell transfusion threshold was as safe as a liberal red cell transfusion threshold (composite outcome of death from any cause, myocardial infarction, stroke or new‐onset renal failure with dialysis at 6 months after surgery).