The synthesis, characterization and antitumor activities of A C-type arsenomolybdate. (February 2019)

• Record Type: Journal Article
• Authors: Wu, Q; Li, J; Hu, X L
• Is Part Of: IOP conference series. Volume 479(2019)
• Publication Date: 2019-02
• Subjects: Materials science -- Periodicals; 620.1105
• DOI: 10.1088/1757-899X/479/1/012027
• Languages: English
• ISSNs: 1757-8981

Abstract

Abstract: A new hetropolyoxometal compound (NH4 )14 Fe0.5 [As2 Fe6 Mo22 O85 (H2 O)]·16H2 O (1) has been synthesized and characterized by elemental analysis, thermal analysis and single crystal X-ray diffraction. Crystal data for 1: Triclinic, P 1, a = 12.6245(4) Å, b = 16.8421(5) Å, c = 27.1396(8) Å, α = 98.892(2)°, β = 91.161(2)°, γ = 104.129(3)°, V = 5518.5(3) Å 3, Z = 2. The structural analysis has revealed that 1 represents a rare example of hexa-iron arsenomolybdate. The inhibitory effects of the compound 1 on A549 (human lung cancer) tumour cells were investigated by MTT assay. It is shown that compared with the reference polyoxometalate-based antitumor agent (NH3 Pri)6 [Mo7 O24 ]·3H2 O (PM-8), 1 present higher antitumor activities.