A phase field approach for bone remodeling based on a second-gradient model. (March 2019)

• Record Type: Journal Article
• Authors: Ganghoffer, J.F.; Rahouadj, R.; Boisse, J.; Schiavi, J.
• Is Part Of: Mechanics research communications. Volume 96(2019)
• Page Start: 37
• Page End: 44
• Publication Date: 2019-03
• Subjects: Bone remodeling -- Phase field -- Diffuse interface -- Strain gradient effects -- Ginzburg–Landau equation; Mechanics, Applied -- Periodicals; Mécanique appliquée -- Périodiques; Mechanics, Applied; Periodicals; 530
• DOI: 10.1016/j.mechrescom.2019.02.007
• Languages: English
• ISSNs: 0093-6413

Abstract

Highlights: A mechanobiological model of bone remodeling is developed involving mineralization in a moving diffuse interface between marrow and the newly formed bone. A scalar valued phase field quantifies the degree of mineralization within the diffuse interface at the level of the bone microstructure. The field equations for the mechanical, chemical, and interfacial phenomena are written under the umbrella of thermodynamics of irreversible processes. A strain gradient model is developed under the umbrella of thermodynamics of irreversible processes to assess the impact of the underlying hierarchical microstructure on the effective response of bone. The Ginzburg–Landau equation satisfied by the phase field is written with a source term accounting for the dissipative microforce and incorporating first and strain gradient energies. Abstract: A mechanobiological model of bone remodeling is developed involving mineralization in a moving diffuse interface separating the marrow containing the bone cells responsible for the remodeling from the newly formed bone. A scalar phase field quantifies the degree of mineralization within the interface at the level of the bone microstructure, varying continuously between the nil lower value (no mineral) and unity for the fully mineralized phase corresponding to new bone. The field equations for the mechanical, chemical, and interfacial phenomena are written under the umbrella of thermodynamics of irreversible processes. A strain gradient model is developed to account for the impact of the underlying hierarchical microstructure on the effective response of bone. Second gradient terms are motivated by the high strain and stress concentrations close to defects, both at mesoscopic and microscopic scales. The combination of the balance equations for the microforce associated to the phase field and the kinetic equations lead to the Ginzburg–Landau equation for by the phase field with a source term accounting for the dissipative microforce.