Organizing pneumonia as the first manifestation of anti-synthetase syndrome. (December 2016)

• Record Type: Journal Article
• Authors: Priyangika, S.; karunarathna, W.; Liyanage, Isurujith; Gunawardana, Methsala; Udumalgala, Sumeda; Rosa, Chamith; Kulatunga, Aruna
• Is Part Of: BMC research notes. Volume 9:Number 1(2016)
• Page Start: 1
• Page End: 3
• Publication Date: 2016-12
• Subjects: Anti-synthetase syndrome -- Interstitial lung disease -- Polymyositis -- Organizing pneumonia -- Anti-JO-1 antibody; Medicine -- Periodicals; Biology -- Periodicals; 610.5
• DOI: 10.1186/s13104-016-2094-3
• Languages: English
• ISSNs: 1756-0500

Abstract

Abstract Background Anti-synthetase syndrome associated interstitial lung disease can occur either simultaneously, before, or after the development of polymyositis/dermatomyositis. Histology of interstitial lung disease can be nonspecific interstitial pneumonia, usual interstitial pneumonia, diffuse alveolar damage, organizing pneumonia. Organizing pneumonia associated anti-synthetase syndrome is a rare finding especially as the first manifestation. Case presentation We report a 41 year old male patient who presented with organizing pneumonia and 2 years following the onset, developed polymyositis with anti-JO-1 antibody positivity. Conclusion It is important to screen patients with organizing pneumonia for anti-synthetase syndrome which can be manifested later.