Expanding the diversity of DNA base modifications with N6-methyldeoxyadenosine. Issue 1 (December 2016)

• Record Type: Journal Article
• Authors: Meyer, Kate; Jaffrey, Samie
• Is Part Of: Genome biology. Volume 17:Issue 1(2016)
• Page Start: 1
• Page End: 4
• Publication Date: 2016-12
• Subjects: Genomes -- Periodicals; Biology -- Periodicals; Molecular biology -- Periodicals; 572.8633
• DOI: 10.1186/s13059-016-0874-7
• Languages: English
• ISSNs: 1474-760X

Abstract

Abstract Vertebrate DNA is subjected to epigenetic base modifications that have been thought to be limited to methylated and other modified forms of cytidine. A recent study shows that methylation of adenine to formN 6 -methyladenine is a rare but readily detectable modification that can be mapped to distinct genomic sites in vertebrates.