A case of pan‐resistant Burkholderia cepacia complex bacteremic pneumonia, after lung transplantation treated with a targeted combination therapy. Issue 2 (1st January 2019)

• Record Type: Journal Article
• Authors: Cantón‐Bulnes, María Luisa; Hurtado Martínez, Ángela; López‐Cerero, Lorena; Arenzana Seisdedos, Ángel; Merino‐Bohorquez, Vicente; Garnacho‐Montero, José
• Is Part Of: Transplant infectious disease. Volume 21:Issue 2(2019)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2019-01-01
• Subjects: bacteraemic pneumonia -- lung transplantation -- pan‐resistant Burkholderia Cepacia complex; Transplantation of organs, tissues, etc -- Complications -- Periodicals; Communicable diseases -- Periodicals; Infection -- Periodicals; 617.01
• DOI: 10.1111/tid.13034
• Languages: English
• ISSNs: 1398-2273

Abstract

Abstract: We describe a case of one patient with cystic fibrosis who developed a pan‐resistant Burkholderia cepacia complex rapidly progressive bacteraemic pneunonia, following bilateral lung transplantation. The patient was treated with a targeted combination antibiotic therapy (meropenem plus ceftazidime/avibactam plus high doses of nebulized colistimethate sodium). Evolution of the disease was complicated by multiple organ system dysfunction. Finally, clinical improvement and microbiological cure was achieved.