Dehydrocurvularin is a potent antineoplastic agent irreversibly blocking ATP-citrate lyase: evidence from chemoproteomics. Issue 29 (21st March 2019)

Record Type:: Journal Article
Title:: Dehydrocurvularin is a potent antineoplastic agent irreversibly blocking ATP-citrate lyase: evidence from chemoproteomics. Issue 29 (21st March 2019)
Main Title:: Dehydrocurvularin is a potent antineoplastic agent irreversibly blocking ATP-citrate lyase: evidence from chemoproteomics
Authors:: Deng, Zhangshuang
Wong, Nai-Kei
Guo, Zhiyong
Zou, Kun
Xiao, Youli
Zhou, Yiqing
Abstract:: Abstract : Dehydrocurvularin irreversibly inhibits human ATP-citrate lyase. Abstract : Natural-product macrolide 10, 11-dehydrocurvularin (DCV ) was revealed to be a potent irreversible inhibitor of ATP-citrate lyase (ACLY) via classical chemoproteomic profiling, which mechanistically illuminates the anti-cancer mode of action ofDCV and its analogues.
Is Part Of:: Chemical communications. Volume 55:Issue 29(2019)
Journal:: Chemical communications
Issue:: Volume 55:Issue 29(2019)
Issue Display:: Volume 55, Issue 29 (2019)
Year:: 2019
Volume:: 55
Issue:: 29
Issue Sort Value:: 2019-0055-0029-0000
Page Start:: 4194
Page End:: 4197
Publication Date:: 2019-03-21
Subjects:: Chemistry -- Periodicals
540
Journal URLs:: http://pubs.rsc.org/en/journals/journalissues/cc ↗
http://www.rsc.org/ ↗
DOI:: 10.1039/c9cc00256a ↗
Languages:: English
ISSNs:: 1359-7345
Deposit Type:: Legaldeposit
View Content:: Available online (eLD content is only available in our Reading Rooms) ↗
Physical Locations:: British Library DSC - 3139.350000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store
Ingest File:: 9817.xml