CRISPR sabotage. Issue 1 (December 2015)

• Record Type: Journal Article
• Authors: van der Oost, John; Brouns, Stan
• Is Part Of: Genome biology. Volume 16:Issue 1(2015)
• Page Start: 1
• Page End: 3
• Publication Date: 2015-12
• Subjects: Genomes -- Periodicals; Biology -- Periodicals; Molecular biology -- Periodicals; 572.8633
• DOI: 10.1186/s13059-015-0820-0
• Languages: English
• ISSNs: 1474-760X

Abstract

Abstract The biological arms race generally involves the rapid co-evolution of anti-virus systems in host organisms and of anti-anti-virus systems in their viral parasites. The CRISPR-Cas system is an example of a prokaryotic immune system in which such co-evolution occurs, as was recently demonstrated by the characterization of a set of viral anti-CRISPR proteins.