Three new diterpenoids from Aralia dumetorum. Issue 4 (3rd April 2019)

• Record Type: Journal Article
• Authors: Li, Yan-Hong; Li, Hong-Rui; Yang, Chun-Tao; Tian, Kai; Yang, Cui; Sun, Jing-Xian; Wang, Wei; Huang, Xiang-Zhong
• Is Part Of: Journal of Asian natural products research. Volume 21:Issue 4(2019)
• Page Start: 308
• Page End: 315
• Publication Date: 2019-04-03
• Subjects: Araliaceae -- Aralia dumetorum -- pimarane -- diterpenoid -- cytotoxicity; Materia medica -- Asia -- Periodicals; Pharmacognosy -- Asia -- Periodicals; Medicinal plants -- Asia -- Periodicals; Medicine, Oriental -- Asia -- Periodicals; 615.321095
• DOI: 10.1080/10286020.2019.1567503
• Languages: English
• ISSNs: 1028-6020

Abstract

Abstract: Three new diterpenoids, dumetoranes A (1 ) and B (2 ), melanocane B (3 ), together with four known ones including melanocane A (4 ), ent -15 S, 16-dihydroxypimar-8(14)-en-19-oic acid (5 ), ent -pimara-8(14), 15-diene-19-oic acid (6 ), and ent -pimara-8(14), 15-diene-19-ol (7 ) were obtained from the ethanol extract of the roots of Aralia dumetorum . Their structure elucidation was achieved by the methods of spectroscopic HRMS, IR, NMR, and by comparison with literature. The cytotoxicities of compounds1 –3 and5 were assayed by in vitro MTT methods. Abstract :