Applications of Synthetic Gene Networks. (September 2015)

• Record Type: Journal Article
• Authors: Wu, Fuqing; Wang, Xiao
• Is Part Of: Science progress. Volume 98:Number 3(2015)
• Page Start: 244
• Page End: 252
• Publication Date: 2015-09
• Subjects: synthetic gene networks -- biological design principles; Science -- Periodicals; Research; Science; Science; Electronic journals; Periodicals; Periodicals; 505
• DOI: 10.3184/003685015X14368807556441
• Languages: English
• ISSNs: 0036-8504

Abstract

Synthetic gene networks have evolved from simple proof-of-concept circuits to complex therapy-oriented networks over the past 15 years. This advancement has greatly facilitated the expansion of the emerging field of synthetic biology. In this review, we highlight the main applications of synthetic gene networks in understanding biological design principles, developing biosensors for diagnosis, producing industrial and biomedical compounds, and treating human diseases. Finally, we outline current challenges and future prospects of synthetic gene networks for advancing practical applications.