Recyclable Cytokines: Recyclable Cytokines on Short and Injectable Polylactic Acid Fibers for Enhancing T‐Cell Function (Adv. Funct. Mater. 14/2019). (1st April 2019)

• Record Type: Journal Article
• Authors: Shin, Hyun Mu; Ju, Youngjun; Kim, Gwanghun; Lee, Jae Won; Seo, Myung Won; Sim, Ji Hyun; Yang, Jusang; Noh, Sora; Kim, Jungbae; Kim, Hang‐Rae
• Is Part Of: Advanced functional materials. Volume 29:Number 14(2019)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2019-04-01
• Subjects: cancer immunotherapy -- cytokine delivery -- electrospun fibers -- enzymatic polydopamine coating -- injectable fibers; Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adfm.201970092
• Languages: English
• ISSNs: 1616-301X

Abstract

Abstract : In article number1808361, Jungbae Kim, Hang‐Rae Kim, and co‐workers inject cytokine‐immobilized short polylactic acid (PLA) fibers (Cyto‐sPLA) near a tumor to reinvigorate nonfunctional T cells. The administration of Cyto‐sPLA fibers kills tumor cells and ultimately effectively inhibits tumor growth. Injectable Cyto‐sPLA fibers have great potential for the development of anticancer therapeutics.