Fabrication and biomedical potential of nanogels: An overview. Issue 6 (13th April 2019)

• Record Type: Journal Article
• Authors: Kaur, Maninderjeet; Sudhakar, Kalvatala; Mishra, Vijay
• Is Part Of: International journal of polymeric materials. Volume 68:Issue 6(2019)
• Page Start: 287
• Page End: 296
• Publication Date: 2019-04-13
• Subjects: Drug delivery -- imaging agent -- nanogels -- polymerization -- therapeutic carrier; Polymers -- Periodicals; Plastics -- Periodicals; 620.19205
• DOI: 10.1080/00914037.2018.1445629
• Languages: English
• ISSNs: 0091-4037

Abstract

ABSTRACT: Nanogels are one of the innovative hydrogel systems that comprise cross-linked polymers of natural or synthetic origin having good water holding capacity. The hydrophilic nature of nanogels possess good water uptake and exhibit controlled, targeted and sustained release. Nanogels show promising features like high biodegradability, biocompatibility, drug loading capacity and good penetration power. This overview mainly focuses on the biomedical applications of nanogels as the drug delivery system, imaging agent, therapeutic carrier, theranostic agent, also its fabrication techniques. In current scenario, nanogels play promising roles to deliver drugs such as anticancer, autoimmune, ophthalmics, anti-microbials, anti-inflammatory, proteins and peptides. GRAPHICAL ABSTRACT: