Control of stem cell response and bone growth on biomaterials by fully non-peptidic integrin selective ligands. (8th February 2019)
- Record Type:
- Journal Article
- Title:
- Control of stem cell response and bone growth on biomaterials by fully non-peptidic integrin selective ligands. (8th February 2019)
- Main Title:
- Control of stem cell response and bone growth on biomaterials by fully non-peptidic integrin selective ligands
- Authors:
- Fraioli, R.
Neubauer, S.
Rechenmacher, F.
Bosch, B. M.
Dashnyam, K.
Kim, J.-H.
Perez, R. A.
Kim, H.-W.
Gil, F. J.
Ginebra, M. P.
Manero, J. M.
Kessler, H.
Mas-Moruno, C. - Abstract:
- Abstract : Integrin selective peptidomimetics tune stem cell behavior in vitro and improve bone formation in rat calvarial defects. Abstract : In this communication we report that anchoring αvβ3 or α5β1 integrin-selective RGD peptidomimetics to titanium efficiently tunes mesenchymal stem cell response in vitro and bone growth in rat calvarial defects. Our results demonstrate that this molecular chemistry-derived approach could be successful to engineer instructive coatings for orthopedic applications.
- Is Part Of:
- Biomaterials science. Volume 7:Number 4(2019)
- Journal:
- Biomaterials science
- Issue:
- Volume 7:Number 4(2019)
- Issue Display:
- Volume 7, Issue 4 (2019)
- Year:
- 2019
- Volume:
- 7
- Issue:
- 4
- Issue Sort Value:
- 2019-0007-0004-0000
- Page Start:
- 1281
- Page End:
- 1285
- Publication Date:
- 2019-02-08
- Subjects:
- Biomedical materials -- Periodicals
610.28 - Journal URLs:
- http://pubs.rsc.org/en/journals/journalissues/bm ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/c8bm01466c ↗
- Languages:
- English
- ISSNs:
- 2047-4830
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 2087.724000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 9732.xml