Comparative study of core- and surface-radiolabeling strategies for the assembly of iron oxide nanoparticle-based theranostic nanocomposites. Issue 13 (19th March 2019)

• Record Type: Journal Article
• Authors: Zhang, Junzhe; Ma, Yuhui; Yang, Wenjiang; Xue, Jingquan; Ding, Yayun; Xie, Changjian; Luo, Wenhe; Gao, Fuping; Zhang, Zhiyong; Zhao, Yuliang; Chai, Zhifang; He, Xiao
• Is Part Of: Nanoscale. Volume 11:Issue 13(2019)
• Page Start: 5909
• Page End: 5913
• Publication Date: 2019-03-19
• Subjects: Nanoscience -- Periodicals; Nanotechnology -- Periodicals; 620.505
• DOI: 10.1039/c9nr00428a
• Languages: English
• ISSNs: 2040-3364

Abstract

Abstract : This study implies a possible overestimation of the labeling stability in previous studies and points out directions for further optimization. Abstract : This work highlights the superiority of the surface-radiolabeling strategy over the core-labeling strategy in the assembly of radioactive iron oxide nanoparticle (IONP)-based nanocomposites for use in multimodal imaging and targeted therapy. It also implies a possible overestimation of the labeling stability in previous studies and points out directions for further optimization.