A case report of placental mesenchymal dysplasia: A rare case of a genetically normal fetus with severe intrauterine growth restriction. Issue 8 (February 2019)

• Record Type: Journal Article
• Authors: Doroftei, Bogdan; Neculai-Valeanu, Sabina; Simionescu, Gabriela; Grab, Delia; Plopa, Natalia; Anton, Emil; Maftei, Radu
• Other Names: NA. section editor.
• Is Part Of: Medicine. Volume 98:Issue 8(2019)
• Publication Date: 2019-02
• Subjects: Beckwith–Wiedemann syndrome -- intrauterine fetal growth restriction -- molar pregnancy -- placental mesenchymal dysplasia; Medicine -- Periodicals; Medicine -- Periodicals; Médecine -- Périodiques; Geneeskunde; Medicine; Periodicals; Periodicals; 610.5
• DOI: 10.1097/MD.0000000000014554
• Languages: English
• ISSNs: 0025-7974

Abstract

Abstract: Rationale: We report a rare case of a pregnant woman with placental mesenchymal dysplasia (PMD) and intrauterine growth restriction (IUGR) with a genetically normal fetus. Patient concerns: A 42-year-old woman Gravida I, Para I with pre-existent uncontrolled hypertension and uterine polyfibromatosis present at 30 weeks of gestation for diminished fetal activity during the last 2 days. Diagnosis: Placental mesenchymal dysplasia associated with intrauterine growth restriction, hypertension, and uterine polyfibromatosis. Intervention: A live male infant was delivered by emergency caesarean section. Outcomes: The infant, weighing 700 g, died 4 days after birth due to a massive intracerebral hemorrhage. Lessons: A careful examination should be done at every ultrasound in case of a fetus with IUGR to exclude some rare cases of placental pathologies. PMD can be a rare cause of IUGR with a genetically normal fetus.