Complex pulmonary arteriovenous fistula in mother and daughter: Case report. Issue 2 (January 2019)

• Record Type: Journal Article
• Authors: Zhang, Xin; Zheng, Mingxia; Li, Xingjian; Yan, Yejun; Yang, Caixia; Zhao, Zhengang; Feng, Yuan; Chen, Mao
• Other Names: NA. section editor.
• Is Part Of: Medicine. Volume 98:Issue 2(2019)
• Publication Date: 2019-01
• Subjects: family -- interventional treatment -- pulmonary arteriovenous fistulas; Medicine -- Periodicals; Medicine -- Periodicals; Médecine -- Périodiques; Geneeskunde; Medicine; Periodicals; Periodicals; 610.5
• DOI: 10.1097/MD.0000000000013922
• Languages: English
• ISSNs: 0025-7974

Abstract

Abstract: Rationale: Complex pulmonary arteriovenous fistula (PAVF) is unusual, and even rarer in 2 members of a family. PAVF may not appear on chest X-ray or computed tomography imaging, especially in asymptomatic patients, and therapy is limited. Herein, PAVFs occurring in a mother and daughter are described, with the current standard methods of diagnosis and treatment of PAVF. Patient concerns: A 34-year-old woman and her 13-year-old daughter presented with light cyanosis of the nail beds but were otherwise asymptomatic, and physical examination was unremarkable. Their arterial oxygen saturation levels were low (80–85%). Diagnoses: Angiography led to a diagnosis of PAVF involving the bilateral lung in both women. Interventions: The combined use of coils with occluder (patent ductus arteriosus, or PDA) to obstruct the fistula. Outcomes: After interventional treatment, the patients' arterial oxygen saturation improved rapidly (90–95%). At 6-month follow-up, the patients' symptoms and oxygen saturation were normal. Lessons: PAVF is an autosomal dominant disease. Here, the characteristics of the 2 patients were very similar. Using detachable coils and then a PDA occluder is a highly efficient method for treating complex PAVFs.