A convenient method for phosphorylation using triallyl phosphite. Issue 32 (5th August 2015)

• Record Type: Journal Article
• Authors: Li, Si-Zhe; Ahmar, Mohammed; Queneau, Yves; Soulère, Laurent
• Is Part Of: Tetrahedron letters. Volume 56:Issue 32(2015)
• Page Start: 4694
• Page End: 4696
• Publication Date: 2015-08-05
• Subjects: Phosphorylation -- Phosphite -- Allyl-protecting groups; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tetlet.2015.06.030
• Languages: English
• ISSNs: 0040-4039

Abstract

Graphical abstract: Abstract: A direct method for the phosphorylation of alcohols, phenols, saccharides and nucleosides using triallyl phosphite is described. From primary or secondary alcohols, the corresponding diallyl-protected phosphorylated compounds are obtained in good to high yields. The method was found to be selective for primary alcohols and to be applicable to diverse simple and functionalized alcohols, including amino acids, carbohydrates and nucleosides.