Spontaneous Improvement of Visual Acuity in a 13-Year-Old Boy with Neuromyelitis Optica Spectrum Disorder. (4th March 2019)

• Record Type: Journal Article
• Authors: Yamaguchi, Keiko; Hayashi, Takaaki; Kiriyama, Akiko; Iida, Kie; Yoshimine, Shoyo; Masuda, Yoichiro; Shikishima, Keigo; Ariizumi, Mitsuko; Takahashi, Genichiro; Nakano, Tadashi
• Is Part Of: Neuro-ophthalmology. Volume 43:Number 2(2019)
• Page Start: 114
• Page End: 119
• Publication Date: 2019-03-04
• Subjects: Juvenile boy -- anti-aquaporin 4 antibody -- optic neuritis -- neuromyelitis optica spectrum disorder -- junctional scotoma; Neuroophthalmology -- Periodicals; 617.7
• DOI: 10.1080/01658107.2018.1483951
• Languages: English
• ISSNs: 0165-8107

Abstract

ABSTRACT: Ophthalmic and MRI evaluations of a 13-year-old boy who reported loss of visual acuity in his right eye demonstrated the presence of unilateral optic neuritis. After serological tests showed positivity for anti-aquaporin 4 antibody, he was diagnosed with neuromyelitis optica spectrum disorder. Encephalopathy and myelitis were not observed. Since his unilateral optic neuritis was considered to reflect mild disease activity, only follow-up observations were performed. Visual acuity and central scotoma improved 1 week after the first examination. In the absence of any specific treatments, good visual acuity has remained for 20 months, with no relapse of optic neuritis.