Monitoring Knee Biomechanics in Patients Undergoing Anterior Cruciate Ligament Reconstruction: How Joint Loading Affects Cartilage Quality. (2019)

• Record Type: Journal Article
• Authors: Marchiori, G.; Cassiolas, G.; Berni, M.; Lopomo, N.F.; Valente, G.; Signorelli, C.; Bontempi, M.; Zaffagnini, S.
• Is Part Of: Materials today. Volume 7:Part 1(2019)
• Page Start: 522
• Page End: 528
• Publication Date: 2019
• Subjects: Multi-Body Modelling -- Dynamic RSA -- ACL Reconstruction -- MRI T2 Mapping -- Articular Cartilage; Materials science -- Congresses -- Periodicals; 620.1
• DOI: 10.1016/j.matpr.2018.12.003
• Languages: English
• ISSNs: 2214-7853

Abstract

Abstract: Rupture of anterior cruciate ligament (ACL) is a common injury, generally treated by reconstruction surgery. Despite good clinical outcomes, achieving a long-term success for this procedure is still a challenge: young patients could face in fact early degenerative processes, including knee osteoarthritis (OA). The altered biomechanics of the reconstructed joint could affect knee anatomical structures varying – for instance – the loads on the intra-articular cartilage, definitely inducing its degeneration. To better understand the factors that can compromise the long-term success of this procedure, this study investigated the ACL transtibial reconstruction effects on overall knee biomechanics and on articular cartilage, by integrating dynamic radiostereophotogrammetry, inferior limb multi-body modelling and MRI T2 mapping, in order to correlate knee joint loads to its physiopathological status