How do species, population and active ingredient influence insecticide susceptibility in Culicoides biting midges (Diptera: Ceratopogonidae) of veterinary importance?. Issue 1 (December 2015)

• Record Type: Journal Article
• Authors: Venail, Roger; Lhoir, Jonathan; Fall, Moussa; del Río, Ricardo; Talavera, Sandra; Labuschagne, Karien; Miranda, Miguel; Pagès, Nonito; Venter, Gert; Rakotoarivony, Ignace; Allène, Xavier; Scheid, Bethsabée; Gardès, Laëtitia; Gimonneau, Geoffrey; Lancelot, Renaud; Garros, Claire; Cêtre-Sossah, Catherine; Balenghien, Thomas; Carpenter, Simon; Baldet, Thierry
• Is Part Of: Parasites & vectors. Volume 8:Issue 1(2015)
• Page Start: 1
• Page End: 9
• Publication Date: 2015-12
• Subjects: Culicoides imicola -- Culicoides obsoletus -- Culicoides nubeculosus -- Insecticide susceptibility -- Pyrethroids -- Organophosphates -- Vector control; Parasitism -- Periodicals; Parasites -- Periodicals; Vector-pathogen relationships -- Periodicals; Animals as carriers of disease -- Periodicals; Insects as carriers of disease -- Periodicals; 616.96
• DOI: 10.1186/s13071-015-1042-8
• Languages: English
• ISSNs: 1756-3305

Abstract

Abstract Background Culicoides biting midges are biological vectors of internationally important arboviruses of livestock and equines. Insecticides are often employed againstCulicoides as a part of vector control measures, but systematic assessments of their efficacy have rarely been attempted. The objective of the present study is to determine baseline susceptibility of multipleCulicoides vector species and populations in Europe and Africa to the most commonly used insecticide active ingredients. Six active ingredients are tested: three that are based on synthetic pyrethroids (alpha-cypermethrin, deltamethrin and permethrin) and three on organophosphates (phoxim, diazinon and chlorpyrifos-methyl). Methods Susceptibility tests were conducted on 29, 064 field-collected individuals ofCulicoides obsoletus Meigen, Culicoides imicola Kieffer and a laboratory-rearedCulicoides nubeculosus Meigen strain using a modified World Health Organization assay. Populations ofCulicoides were tested from seven locations in four different countries (France, Spain, Senegal and South Africa) and at least four concentrations of laboratory grade active ingredients were assessed for each population. Results The study revealed that insecticide susceptibility varied at both a species and population level, but that broad conclusions could be drawn regarding the efficacy of active ingredients. Synthetic pyrethroid insecticides were found to inflict greater mortality than organophosphate active ingredients and the colony strain ofC. nubeculosus was significantly more susceptible than field populations. Among the synthetic pyrethroids, deltamethrin was found to be the most toxic active ingredient for all species and populations. Conclusions The data presented represent the first parallel and systematic assessment ofCulicoides insecticide susceptibility across several countries. As such, they are an important baseline reference to monitor the susceptibility status ofCulicoides to current insecticides and also to assess the toxicity of new active ingredients with practical implications for vector control strategies.