Cover Feature: Convenient Entry to 18F‐Labeled Amines through the Staudinger Reduction (Eur. J. Org. Chem. 8/2019). Issue 8 (15th February 2019)

• Record Type: Journal Article
• Authors: Stéen, E. Johanna L.; Shalgunov, Vladimir; Denk, Christoph; Mikula, Hannes; Kjær, Andreas; Kristensen, Jesper L.; Herth, Matthias M.
• Is Part Of: European journal of organic chemistry. Issue 8(2019)
• Page Start: 1686
• Page End: 1686
• Publication Date: 2019-02-15
• Subjects: Chemistry, Organic -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1002/ejoc.201900228
• Languages: English
• ISSNs: 1434-193X

Abstract

Abstract : The Cover Feature shows how the skill of millinery can be used to change the style of a hat and adjust it to the tastes of hat lovers with diverse preferences. Likewise, azides labeled with fluorine‐18 can be easily converted into amines via the Staudinger reduction. These 18F‐labeled synthons can be indirectly introduced into a wide range of substrates by various methods. This provides a flexible strategy for the development of 18F‐labeled radiopharmaceuticals, useful in positron emission tomography (PET) imaging. More information can be found in theCommunication by M. M. Herth et al.