Two new secolignans from the roots of Urtica fissa. Issue 2 (1st February 2019)

• Record Type: Journal Article
• Authors: Lu, Xuan; Li, Xue-Qing; Qin, Hai-Hong; Feng, Bao-Min; Cheng, Xing-Hua; Yang, Qing-Xiong; Yu, Da-Yong; Shi, Li-Ying; Yu, Zong-Xia; Fang, Xue-Xun
• Is Part Of: Journal of Asian natural products research. Volume 21:Issue 2(2019)
• Page Start: 165
• Page End: 170
• Publication Date: 2019-02-01
• Subjects: Secolignans -- Urtica fissa -- structual analysis -- neuraminidases; Materia medica -- Asia -- Periodicals; Pharmacognosy -- Asia -- Periodicals; Medicinal plants -- Asia -- Periodicals; Medicine, Oriental -- Asia -- Periodicals; 615.321095
• DOI: 10.1080/10286020.2017.1411347
• Languages: English
• ISSNs: 1028-6020

Abstract

Abstract: Two new secolignans, 3, 4- trans -3-hydroxymethyl-4-[bis(4-hydroxy-3- methoxyphenyl)methyl]butyrolactone (1 ) and 3, 4- trans -3-hydroxymethyl-4- [bis(3, 4-dimethoxyphenyl)methyl]butyrolactone (2 ) have been isolated from the roots of Urtica fissa E.Pritz. Their structures were determined on the basis of spectroscopic methods, especially 1 H NMR, 13 C NMR, 2D NMR, and HR-ESI-MS. The inhibitory effects on N1 and N2, two subtypes of neuraminidases (NAs), of these two compounds were assayed. Abstract :