Radiochemical isolation method for the production of 52gMn from natCr for accelerator targets. (April 2019)

• Record Type: Journal Article
• Authors: Barrett, Kendall E.; Aluicio-Sarduy, Eduardo; Olson, Aeli P.; Kutyreff, Christopher J.; Ellison, Paul A.; Barnhart, Todd E.; Nickles, Robert J.; Engle, Jonathan W.
• Is Part Of: Applied radiation and isotopes. Volume 146(2019:Apr.)
• Page Start: 99
• Page End: 103
• Publication Date: 2019-04
• Subjects: 52gMn -- DOTA -- Precipitation -- Cyclotron -- Radionuclide production; Radiology -- Periodicals; Radiation -- Industrial applications -- Periodicals; Nuclear chemistry -- Periodicals; Internet resource; Periodical; 660.298
• DOI: 10.1016/j.apradiso.2019.01.025
• Languages: English
• ISSNs: 0969-8043

Abstract

Abstract: We report a novel, precipitation-based method for the isolation of Mn from Cr targets for cyclotron production of 52g Mn. The separation produces no-carrier-added 52g Mn with a decay corrected radiochemical yield of 85 ± 3% and apparent molar activity for DOTA of 1.3 GBq/μmol. This method reduces stable metallic impurities in the purified 52g Mn compared to previously reported chromatographic methods. Highlights: Radiochemical separation using a 2-phase precipitation method and single extraction chromatography column. Separation strategy for production no-carrier-added 52g Mn. Process allows for chelation studies with DOTA.