An Extremely Rare Case of Postpartum Gestational Choriocarcinoma with Long-Term Survival. (November 2017)

• Record Type: Journal Article
• Authors: Vincent, Marjolaine; Court-Fortune, Isabelle; Karpathiou, Georgia; Froudarakis, Marios E.; Vergnon, Jean-Michel
• Is Part Of: Tumori. Volume 103:(2017)Supplement 1
• Page Start: S16
• Page End: S18
• Publication Date: 2017-11
• Subjects: Choriocarcinoma -- Chorionic gonadotropic hormone -- Intracardiac -- Metastasis -- Postpartum; Cancer -- Periodicals; 616.994
• DOI: 10.5301/TJ.5000660
• Languages: English
• ISSNs: 0300-8916

Abstract

Gestational choriocarcinomas are highly malignant tumors with elevated serum human chorionic gonadotropin (hCG) levels. We report an extremely rare case of a 27-year-old woman who presented 4 months after normal delivery, with pulmonary, renal and intracardiac metastases of a choriocarcinoma. No primary uterine tumor was found. She was surgically treated for the renal and cardiac metastases as well as with cisplatin-etoposide chemotherapy. No recurrence has been observed 16 years after initial diagnosis, and the patient was able to have a second child. This case report shows that appropriate treatment of metastatic gestational choriocarcinoma can cure the patient without compromising her fertility.