A new prenylated stilbene derivative from the roots of Cudrania tricuspidata. (1st May 2013)

• Record Type: Journal Article
• Authors: Shan, Wei-Guang; Shi, Ling-Ling; Ying, You-Min; Hou, Xiao-Rong; Zhan, Zha-Jun
• Is Part Of: Journal of chemical research. Volume 37:Number 5(2013)
• Page Start: 285
• Page End: 286
• Publication Date: 2013-05-01
• Subjects: Chemistry -- Research -- Periodicals; Chemistry -- Periodicals; 540.5
• DOI: 10.3184/174751913X13647406965542
• Languages: English
• ISSNs: 1747-5198

Abstract

A new prenylated stilbene, 2-dimethylallyl-3, 5, 2′, 4′-tetrahydroxy-(E)-stilbene, cudrastilbene, and five known compounds, oxyresveratrol, naringenin, steppogenin, aromadendrin, and genistein were isolated from the roots of Cudrania tricuspidata. The structure of the new compound was established by spectroscopic methods. All the compounds were evaluated for their cytotoxicity against three human tumour cell lines (HepG2, HCT-116, and SGC-7901). Cudrastilbene showed weak cytotoxic activity against the HepG2 cell line with an IC50 of 40.19 μM.