Ammonium chloride catalysed one-pot multicomponent synthesis of 1, 8-dioxo-octahydroxanthenes and N-aryl-1, 8-dioxodecahydroacridines under solvent free conditions. (1st December 2014)

• Record Type: Journal Article
• Authors: Banerjee, Bubun; Brahmachari, Goutam
• Is Part Of: Journal of chemical research. Volume 38:Number 12(2014)
• Page Start: 745
• Page End: 750
• Publication Date: 2014-12-01
• Subjects: Chemistry -- Research -- Periodicals; Chemistry -- Periodicals; 540.5
• DOI: 10.3184/174751914X14177132210020
• Languages: English
• ISSNs: 1747-5198

Abstract

A simple, straightforward and highly efficient protocol has been developed for the one-pot multicomponent synthesis of 1, 8-dioxo-octahydroxanthenes from the reaction of aromatic aldehydes and dimedone, and also N-aryl-1, 8-dioxodecahydroacridines from aromatic aldehydes, dimedone and aromatic amines in excellent yields using ammonium chloride as a low-cost and non-toxic eco-friendly catalyst under solvent-free conditions. The salient features of the present protocol are the operational simplicity, clean reaction profiles, excellent yields, high atom-economy, relatively short reaction-time as well as the use of inexpensive and environmentally benign catalyst.