RhIII‐Catalyzed Straightforward Synthesis of Benzophenanthroline and Benzophenanthrolinone Derivatives using Anthranils. Issue 12 (5th February 2019)

• Record Type: Journal Article
• Authors: Biswas, Aniruddha; Sarkar, Souradip; Samanta, Rajarshi
• Is Part Of: Chemistry. Volume 25:Issue 12(2019)
• Page Start: 3000
• Page End: 3004
• Publication Date: 2019-02-05
• Subjects: amination -- anthranil -- annulation -- N-PAHs -- rhodium -- step-economic synthesis; Chemistry -- Periodicals; 540
• DOI: 10.1002/chem.201806373
• Languages: English
• ISSNs: 0947-6539

Abstract

Abstract: An efficient pot‐economic and step‐economic Rh III ‐catalyzed site‐selective direct amination/annulation strategy was developed for the synthesis of benzophenanthroline derivatives using quinoline N‐oxides and anthranils. The method was further extended to the synthesis of nitrogen‐containing extended π‐conjugated benzophenanthrolinone derivatives. Late‐stage functionalizations of cinchonidine and cinchophen derivatives and synthesis of a bioactive quinolino‐indole were achieved. Abstract : An efficient pot‐economic and step‐economic Rh III ‐catalyzed site‐selective direct amination/annulation strategy was developed for the synthesis of benzophenanthroline derivatives using quinoline N ‐oxides and anthranils (see scheme).