Hypersensitivity reactions to folic acid: Three case reports and a review of the literature. (December 2018)

• Record Type: Journal Article
• Authors: Nucera, Eleonora; Aruanno, Arianna; Mezzacappa, Simona; Pascolini, Lucilla; Buonomo, Alessandro; Schiavino, Domenico
• Is Part Of: International journal of immunopathology and pharmacology. Volume 32:Mar./Dec.(2018)
• Publication Date: 2018-12
• Subjects: drug allergy -- fixed drug eruption -- urticaria; Immunopathology -- Periodicals; Pharmacology -- Periodicals; Inflammation -- Periodicals; 615.1
• DOI: 10.1177/2058738418817704
• Languages: English
• ISSNs: 0394-6320

Abstract

Adverse reactions to folic acid are an extremely uncommon condition; we present three cases of hypersensitivity to folic acid with different symptomatic manifestations. In the first and second cases, we made the diagnosis of IgE-mediate-type allergy to folic acid, while in the third one, we found a fixed drug eruption to folic acid.