Destabilization of DNA through interstrand crosslinking by UO22+. Issue 14 (15th January 2019)
- Record Type:
- Journal Article
- Title:
- Destabilization of DNA through interstrand crosslinking by UO22+. Issue 14 (15th January 2019)
- Main Title:
- Destabilization of DNA through interstrand crosslinking by UO22+
- Authors:
- Rossberg, André
Abe, Takaya
Okuwaki, Koji
Barkleit, Astrid
Fukuzawa, Kaori
Nakano, Tatsuya
Mochizuki, Yuji
Tsushima, Satoru - Abstract:
- Abstract : UO2 2+ was shown to form an interstrand crosslink between two different strands of a single DNA molecule. Abstract : UO2 2+ was shown to form an interstrand crosslink between two different strands of a single DNA molecule. This crosslink hardly affected the hydrogen bonds between nucleobase pairs but destabilized the π–π stacking between the two nucleobases in the vicinity of UO2 2+ -bound phosphate. Thereby, the fragility of the DNA backbone increased upon UO2 2+ binding.
- Is Part Of:
- Chemical communications. Volume 55:Issue 14(2019)
- Journal:
- Chemical communications
- Issue:
- Volume 55:Issue 14(2019)
- Issue Display:
- Volume 55, Issue 14 (2019)
- Year:
- 2019
- Volume:
- 55
- Issue:
- 14
- Issue Sort Value:
- 2019-0055-0014-0000
- Page Start:
- 2015
- Page End:
- 2018
- Publication Date:
- 2019-01-15
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://pubs.rsc.org/en/journals/journalissues/cc ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/c8cc09329f ↗
- Languages:
- English
- ISSNs:
- 1359-7345
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3139.350000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 9536.xml