Molecular Modeling: Modeling Interactions between Liposomes and Hydrophobic Nanosheets (Small 6/2019). Issue 6 (8th February 2019)

• Record Type: Journal Article
• Authors: Li, Zhen; Zhang, Yonghui; Ma, Jiale; Meng, Qiangqiang; Fan, Jun
• Is Part Of: Small. Volume 15:Issue 6(2019)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2019-02-08
• Subjects: cytotoxicity -- lipid membranes -- liposomes -- molecular dynamics simulations -- nanosheets; Nanotechnology -- Periodicals; Nanoparticles -- Periodicals; Microtechnology -- Periodicals; 620.5
• DOI: 10.1002/smll.201970034
• Languages: English
• ISSNs: 1613-6810

Abstract

Abstract : Although 2D nanomaterials have shown promising biomedical applications, their sharp edges and hydrophobic interaction with phospholipids could wreak havoc with cell membranes. In article number1804992, Jun Fan and co‐workers investigate molecular insights into the interaction between hydrophobic nanosheets and lipid membranes using molecular dynamics simulations. Many molecule motions and thermodynamics are revealed, expanding knowledge of the behavior of 2D nanomaterials in biosystems.