Lipid‐Coated Microbubbles: Enhanced Osteogenic Differentiation of Human Mesenchymal Stem Cells Using Microbubbles and Low Intensity Pulsed Ultrasound on 3D Printed Scaffolds (Adv. Biosys. 2/2019). Issue 2 (12th February 2019)

• Record Type: Journal Article
• Authors: Osborn, Jenna; Aliabouzar, Mitra; Zhou, Xuan; Rao, Raj; Zhang, Lijie Grace; Sarkar, Kausik
• Is Part Of: Advanced biosystems. Volume 3:Issue 2(2019)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2019-02-12
• Subjects: microbubbles -- osteogenesis -- stem cells -- tissue engineering -- ultrasound; Biological systems -- Periodicals; Biotechnology -- Periodicals; Bioengineering -- Periodicals; Biomedical engineering -- Periodicals; Biological Science Disciplines; Periodicals; Periodicals; 660.6
• DOI: 10.1002/adbi.201970021
• Languages: English
• ISSNs: 2366-7478

Abstract

Abstract : In article number1800257, Kausik Sarkar and co‐workers explore a novel application of microbubbles along with low intensity pulsed ultrasound (LIPUS) in bone tissue engineering. The lipid coated microbubbles enhance proliferation and osteogenic differentiation of human mesenchymal stem cells on 3D printed poly(lactic) acid scaffolds. The effect is found to be greater than that with LIPUS alone. It promises great therapeutic potential for the treatment of bone injuries that afflict millions worldwide with debilitating pain and crippling disabilities.