Glucose‐Responsive Insulin Delivery: Microneedle‐Array Patch Fabricated with Enzyme‐Free Polymeric Components Capable of On‐Demand Insulin Delivery (Adv. Funct. Mater. 7/2019). (12th February 2019)

• Record Type: Journal Article
• Authors: Chen, Siyuan; Matsumoto, Hiroko; Moro‐oka, Yuki; Tanaka, Miyako; Miyahara, Yuji; Suganami, Takayoshi; Matsumoto, Akira
• Is Part Of: Advanced functional materials. Volume 29:Number 7(2019)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2019-02-12
• Subjects: boronate hydrogel -- closed‐loop -- glucose‐responsive insulin delivery -- microneedles -- silk fibroin; Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adfm.201970044
• Languages: English
• ISSNs: 1616-301X

Abstract

Abstract : In article number1807369, Akira Matsumoto and co‐workers report an electronics‐free, enzyme‐free, and nanoparticle‐free smart artificial on‐skin pancreas, which is a hybrid microneedle‐array patch fabricated with a glucose‐sensitive boronate‐hydrogel and biocompatible silk fibroin semi‐interpenetrating network. This microneedles‐array patch could mimic the functionality of the pancreas and provide on‐demand insulin delivery in a safe, painless, and convenient way.