Lactic and lactobionic acids as typically moisturizing compounds. (30th September 2018)

• Record Type: Journal Article
• Authors: Algiert‐Zielińska, Barbara; Mucha, Paulina; Rotsztejn, Helena
• Is Part Of: International journal of dermatology. Volume 58:Number 3(2019)
• Page Start: 374
• Page End: 379
• Publication Date: 2018-09-30
• Subjects: Dermatology -- Periodicals; 616.5
• DOI: 10.1111/ijd.14202
• Languages: English
• ISSNs: 0011-9059

Abstract

Abstract: Background: Recently more attention has been drawn to alpha hydroxy and polyhydroxy acids (AHA and PHA) due to their excellent moisturizing and antioxidant properties. These compounds are very beneficial in terms of both cosmetic and dermatological treatments. Objective: The aim of this study was an assessment of moisturizing properties of lactobionic and lactic acids based on available literature. Methods: Literature review using scientific databases: PubMed, Medline (EBSCO), Medline Complete, Karger, Springer/ICM, SpringerLink/online, Wiley Online Library. Results and Conclusions: Through their construction, alpha AHA and PHA are able to bind large amounts of water and act as potent antioxidant agents through inhibition of matrix metalloproteinases and strong chelating properties. Another important characteristic is the maintenance of the epidermal barrier integrity during application of lactic acid (LAC) and lactobionic acid (LA) and thus the opportunity to use them on sensitive skin types including couperose skin.