Bunyaviruses: Single‐Particle Tracking Reveals the Sequential Entry Process of the Bunyavirus Severe Fever with Thrombocytopenia Syndrome Virus (Small 6/2019). Issue 6 (8th February 2019)

• Record Type: Journal Article
• Authors: Liu, Jia; Xu, Mingyue; Tang, Bo; Hu, Liangbo; Deng, Fei; Wang, Hualin; Pang, Dai‐Wen; Hu, Zhihong; Wang, Manli; Zhou, Yiwu
• Is Part Of: Small. Volume 15:Issue 6(2019)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2019-02-08
• Subjects: clathrin -- membrane fusion -- quantum dots -- severe fever with thrombocytopenia syndrome virus (SFTSV) -- single‐particle tracking; Nanotechnology -- Periodicals; Nanoparticles -- Periodicals; Microtechnology -- Periodicals; 620.5
• DOI: 10.1002/smll.201970032
• Languages: English
• ISSNs: 1613-6810

Abstract

Abstract : In article number1803788, Manli Wang, Yiwu Zhou, and co‐workers systematically dissect the dynamic entry process of an emerging tick‐borne bunyavirus, severe fever with thrombocytopenia syndrome virus (SFTSV), by using multicolor tracking of quantum dot‐labeled single‐particles. SFTSV is internalized into clathrin‐coated pits, further delivered to endosomes and finally fused at an approximate pH of 5.6 within the late endosomes.