Biomimetic Gradient: A Microfluidic Model with Hydrogel Barriers for the Construction of Shear‐Free Attractive and Repulsive Cue Gradients (Adv. Mater. Technol. 2/2019). Issue 2 (8th February 2019)

• Record Type: Journal Article
• Authors: Liu, Wenming; Han, Kai; Sun, Meilin; Huang, Zhongchao; Wang, Jinyi
• Is Part Of: Advanced materials technologies. Volume 4:Issue 2(2019)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2019-02-08
• Subjects: axon guidance -- biomimetic gradient integration -- hydrogel -- microfluidics -- neurodevelopment; Materials science -- Periodicals; Technological innovations -- Periodicals; Materials science; Technological innovations; Periodicals; 620.1105
• DOI: 10.1002/admt.201970013
• Languages: English
• ISSNs: 2365-709X

Abstract

Abstract : A microfluidic approach for the integration of multiple biochemical concentration gradients in a single microfluidic device is presented in article number1800434, by Wenming Liu, Jinyi Wang, and co‐workers. The employment of multidirectional hydrogel barriers permits a facile, stable, and long‐term microfluidic production of shear‐free single and double biochemical gradients. Multi‐gradient microfluidics provides a prototypical platform to perform on‐chip biomimetic neuronal manipulation and analysis for the exploration of neurogenesis and development as well as neuro‐regeneration.