Catalytic and Electron Conducting Carbon Nanotube–Reinforced Lysozyme Crystals. (7th December 2018)

• Record Type: Journal Article
• Authors: Contreras‐Montoya, Rafael; Escolano, Guillermo; Roy, Subhasish; Lopez‐Lopez, Modesto T.; Delgado‐López, Jose M.; Cuerva, Juan M.; Díaz‐Mochón, Juan J.; Ashkenasy, Nurit; Gavira, José A.; Álvarez de Cienfuegos, Luis
• Is Part Of: Advanced functional materials. Volume 29:Number 5(2019)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2018-12-07
• Subjects: biomaterials -- carbon nanotubes -- composite materials -- protein crystals -- supramolecular hydrogels; Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adfm.201807351
• Languages: English
• ISSNs: 1616-301X

Abstract

Abstract: Novel reinforced cross‐linked lysozyme crystals containing homogeneous dispersions of single‐walled carbon nanotubes bundles (SWCNTs) are produced and characterized. The incorporation of SWCNTs inside lysozyme crystals gives rise to reinforced composite materials with tunable mechanical strength and electronic conductivity, while preserving the crystal quality and morphology. These reinforced crystals show increased catalytic activity at higher temperatures, being active even above the denaturation temperature. The electron transport through the crystals is linked to the content and distribution of SWCNT bundles inside the crystals. The electron conduction through the crystals is isotropic and very efficient, presenting high conductivity values up to 600 nS at very low (0.05 wt%) SWCNT concentration. To obtain these crystals, a new protocol based on the in situ crystallization of lysozyme in composite SWCNT–peptide hydrogels is developed. These peptide hydrogels are able to homogeneously disperse bundles of hydrophobic SWCNTs allowing first, the crystallization of the enzyme lysozyme and second, transferring the new properties of the inorganic component to the crystals. Taken together, these composite crystals represent an example of the versatility of proteins as biological substrates in the generation of novel functional materials, opening the door to use them in catalysis and bioelectronics at macroscale. Abstract : Novel composite materials based on the incorporation of single‐walled carbon nanotubes inside lysozyme crystals are produced. The inclusion of carbon nanotubes gives rise to crystals with tunable mechanical strength and electronic conductivity. The catalytic activity of these reinforced crystals improves at higher temperature. These crystals are obtained by an in situ lysozyme crystallization in composite peptide–carbon nanotube hydrogels.