Designing dual-functionalized carbon nanotubes with high blood–brain-barrier permeability for precise orthotopic glioma therapy. Issue 5 (30th November 2018) - You, Yuanyuan
Abstract : Herein we synthesize a cell penetrating peptide- and cancer-targeted molecule-functionalized multi-walled carbon nanotube for precise orthotopic glioma therapy. Abstract : Herein we designed and synthesized a cell penetrating peptide- and cancer-targeted molecule-functionalized multi-walled carbon nanotube for precise orthotopic glioma therapy. In addition to reduced toxicity, this nanosystem exhibited enhanced cancer recognition, blood–brain barrier (BBB) penetration, and anticancer activity through increased ROS production.