Acylsilane directed aromatic C–H alkenylations by ruthenium catalysis. Issue 6 (21st December 2018)

• Record Type: Journal Article
• Authors: Lu, Xiunan; Shen, Cong; Meng, Keke; Zhao, Li; Li, Tingyan; Sun, Yaling; Zhang, Jian; Zhong, Guofu
• Is Part Of: Chemical communications. Volume 55:Issue 6(2019)
• Page Start: 826
• Page End: 829
• Publication Date: 2018-12-21
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c8cc08250b
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : A ruthenium-catalyzed site- and stereo-selective C–H alkenylation of aroylsilanes with electron-deficient alkenes was developed, leading to styrenes bearing acylsilane. Abstract : A ruthenium-catalyzed C–H alkenylation of aroylsilanes with electron-deficient alkenes was developed, using acylsilane as the directing group. The mild reaction conditions enable the tolerance of a wide scope of functionalities such as OMe, F, Cl, Br and CF3, providing a convenient and highly effective method for the synthesis of styrene derivatives bearing acylsilane. Steroid and heterocycles such as furan and thiophene were also well tolerated. Furthermore, acylsilane was efficiently converted to the corresponding aldehyde or carboxylic acid.