Accuracy of age-adjusted D-dimer to rule out deep vein thrombosis in the elderly. Issue 174 (February 2019)

• Record Type: Journal Article
• Authors: Riva, Nicoletta; Righini, Marc; Camporese, Giuseppe; Iotti, Matteo; Bucherini, Eugenio; Kamphuisen, Pieter W.; Verhamme, Peter; Douketis, James D.; Tonello, Chiara; Prandoni, Paolo; Ageno, Walter
• Is Part Of: Thrombosis research. Issue 174(2019)
• Page Start: 148
• Page End: 150
• Publication Date: 2019-02
• Subjects: CI confidence interval -- CUS compression ultrasonography -- DD D-dimer -- DVT deep vein thrombosis -- PE pulmonary embolism -- PTP pre-test probability -- VTE venous thromboembolism; Algorithms -- D-dimer -- Diagnosis -- Elderly -- Ultrasonography -- Venous thrombosis; Thrombosis -- Periodicals; 616.135
• DOI: 10.1016/j.thromres.2018.12.024
• Languages: English
• ISSNs: 0049-3848

Abstract

Highlights: The PALLADIO algorithm combined PTP with DD to drive the use of CUS in patients with suspected DVT. The use of age-adjusted DD cut-offs has been recently proposed to increase DD specificity. The age-adjusted DD in elderly outpatients with unlikely PTP reduced the need of CUS by almost 9%. No symptomatic VTE during the 3-month follow-up occurred in this group of patients.