Comparing Patient Demographics and Tumor Characteristics of HIV-Positive and HIV–Negative Patients with Cancer in South Carolina. (9th May 2018)

• Record Type: Journal Article
• Authors: Hallowell, Benjamin D.; Kintziger, Kristina W.; Duffus, Wayne A.; Vena, John E.; Robb, Sara W.
• Is Part Of: Journal of the International Association of Providers of AIDS Care. Volume 17(2018)
• Publication Date: 2018-05-09
• Subjects: HIV -- AIDS -- cancer -- malignancies -- AIDS-related opportunistic infections -- health disparities; AIDS (Disease) -- Periodicals; 616.9792
• DOI: 10.1177/2325958218773766
• Languages: English
• ISSNs: 2325-9574

Abstract

We compared the demographic and disease characteristics of HIV-positive (HIV+) and HIV-negative (HIV−) individuals with a diagnosis of cancer in South Carolina. HIV-positive patients with cancer were reflective of the HIV+ caseload in South Carolina, with HIV+ patients with cancer more likely to be male (odds ratio [OR]: 2.78: 95% confidence interval [CI]: 2.33-3.32), black (OR: 7.68; 95% CI: 6.52-9.06), and younger at cancer diagnosis (OR: 0.92; 95% CI: 0.91-0.92). Controlling for year of birth, HIV+ patients with cancer did not receive cancer diagnoses at a younger age than HIV− controls. HIV-positive individuals did not have more advanced tumor stages or grades at cancer diagnosis; however, after controlling for other factors, HIV+ individuals were still more likely to be deceased at follow-up (OR: 2.64; 95% CI: 2.20-3.17) when compared to HIV− controls. Future studies should use survival analysis methods to identify the characteristics that shorten survival among HIV+ patients with cancer.