Immune Checkpoint Inhibitors: Anti-NKG2A Antibodies on Board. Issue 2 (February 2019)
- Record Type:
- Journal Article
- Title:
- Immune Checkpoint Inhibitors: Anti-NKG2A Antibodies on Board. Issue 2 (February 2019)
- Main Title:
- Immune Checkpoint Inhibitors: Anti-NKG2A Antibodies on Board
- Authors:
- Mingari, Maria Cristina
Pietra, Gabriella
Moretta, Lorenzo - Abstract:
- Abstract : Antibodies directed towards checkpoint inhibitors have unveiled extraordinary potential in cancer therapy. An article by the Vivier group ( Cell 2018;175:1731–1743) shows that blocking the HLA-E-specific NKG2A inhibitory receptor, expressed by NK and inducible in T cells, results in benefits against poor prognosis tumors. Moreover, NKG2A and PD-1/PD-L1 mAb combinations unleash tumor-specific T cell proliferation and memory.
- Is Part Of:
- Trends in immunology. Volume 40:Issue 2(2019)
- Journal:
- Trends in immunology
- Issue:
- Volume 40:Issue 2(2019)
- Issue Display:
- Volume 40, Issue 2 (2019)
- Year:
- 2019
- Volume:
- 40
- Issue:
- 2
- Issue Sort Value:
- 2019-0040-0002-0000
- Page Start:
- 83
- Page End:
- 85
- Publication Date:
- 2019-02
- Subjects:
- Immunology -- Periodicals
571.96 - Journal URLs:
- http://www.sciencedirect.com/science/journal/14714906 ↗
http://www.elsevier.com/journals ↗ - DOI:
- 10.1016/j.it.2018.12.009 ↗
- Languages:
- English
- ISSNs:
- 1471-4906
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 9049.630500
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 9460.xml